Human Heart Valves: An Ideal Choice for Children

Introduction

The use of heart valves in pediatric surgeries, especially for congenital heart defects, is crucial. Human heart valves, also known as allografts, are harvested from human heart tissue donations and provide a better alternative to artificial and animal-derived valves due to their compatibility with the body and longer lifespan. This article, based on insights from Dr. Mohammad Ali Navabi, a specialist in cardiac surgery, discusses the benefits, applications, and future of human heart valves in pediatric heart surgeries, particularly in conditions like Tetralogy of Fallot.

In this video, Dr. Navabi, a pediatric cardiac surgeon, shares his insights on the ideal role of human heart valves in treating congenital heart defects. In a recent surgery, Dr. Navabi replaced a heart valve in a child with Tetralogy of Fallot, who previously had a full heart repair a decade ago. This child needed a valve replacement due to stenosis and right ventricular outflow obstruction.

Benefits of Using Human Valves (Allograft/Homograft)

• High Compatibility with the Body:

Human valves are derived from natural heart tissue, reducing the risk of allergic reactions and rejection. They integrate well with the patient’s body, offering a more natural and lasting solution.

• Longer Lifespan:

Human valves typically last 10-15 years, whereas animal-derived valves generally need replacement every 5-7 years. This extended durability is particularly beneficial for children and adolescents whose bodies are still growing.

• Reduced Need for Anticoagulants:

Unlike mechanical valves that require lifelong anticoagulation therapy, human valves generally require only short-term aspirin after surgery. This is especially beneficial for children, teens, and women of childbearing age.

• Lower Risk of Side Effects:

Human valves have a lower risk of blood clot formation compared to artificial valves, contributing to a healthier and more active lifestyle post-surgery.