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The pericardial membrane has two soft surfaces with approximate thicknesses of 0.3 to 0.8 mm. The product is presented to clients in a lyophilized form, after physical, chemical and anzymatic treatments and becoming acellular. It shows no immunologic or immunoreactive feature. Pericardium is commonly used for pericardial defects, dura mater repair, and periodontal reconstruction in procedures such as GBR and GTR surgeries. These soft tissue grafts are derived from the pericardial sac.